产品货号:
Z32551
中文名称:
ACTH/POMC抗体
英文名称:
Anti-ACTH/POMC Antibody (Clone#OTI1B9)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ACTH/POMC Antibody (Clone#OTI1B9) |
指标别名 | proopiomelanocortin;ACTH;CLIP;LPH;MSH;NPP;OBAIRH;POC |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | POMC |
克隆号 | OTI1B9 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human POMC(NP_001030333) produced in HEK293T cell. |
实际分子量 | 26.6KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | This gene encodes a polypeptide hormone precursor that undergoes extensive,tissue-specific,post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases.There are eight potential cleavage sites within the polypeptide precursor and,depending on tissue type and the available convertases,processing may yield as many as ten biologically active peptides involved in diverse cellular functions.The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used;adrenocorticotrophin,essential for normal steroidogenesis and the maintenance of normal adrenal weight,and lipotropin beta are the major end products.In other tissues,including the hypothalamus,placenta,and epithelium,all cleavage sites may be used,giving rise to peptides with roles in pain and energy homeostasis,melanocyte stimulation,and immune modulation.These include several distinct melanotropins,lipotropins,and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides.Mutations in this gene have been associated with early onset obesity,adrenal insufficiency,and red hair pigmentation.Alternatively spliced transcript variants encoding the same protein have been described.[provided by RefSeq,Jul 2008] |
Uniprot ID | P01189 |
基因名全称 | Pro-opiomelanocortin |
推荐稀释比 | Western blot (WB) 1:4000 |
相关搜索:ACTH/POMC抗体,ACTH抗体,POMC单抗,Anti-ACTH/POMC Antibody (Clone#OTI1B9)